h(yun)|ˎI(y)ֹؐǝ{
60 2023-03-18
ϺF(xin)ɭƬôϺF(xin)ɭƬôʹt(y)ˎW(wng)ѼP(gun)ϺF(xin)ɭƬf(shu),ϺF(xin)ɭƬr(ji),ϺF(xin)ɭƬX,ϺF(xin)ɭƬĹЧc,ϺF(xin)ɭƬ÷cˎƷϢȫԃʹ
ƷQ:ϺF(xin)ɭƬ
(zhn)̖(ho):(gu)ˎ(zhn)204H42511
:1.cY(ji)ˎ(lin)mڸͽY(ji)˲ίY(ji)XĤԼ֦UȾ2.mڸͽY(ji)˲A(y)(1)½_\Y(ji)˲ߵļͥɆTн|(2)Y(ji)˾ؼԇ(yn)(PPD)(qing)(yng)ͬr(sh)زX侀zϷM(jn)ԽY(ji)˲̵^(gu)ȥδ^(gu)Ҏ(gu)Y(ji)ί(3)ڽƄL(zhng)ڼίĻijЩѪҺW(wng)(ni)Ƥϵy(tng)(Ѫϲ)Yλθгg(sh)ȻY(ji)˾ؼԇ(yn)(yng)Է(yng)ߡ(4)35q½Y(ji)˾ؼԇ(yn)(yng)ԵĻ(5)֪ɞHIVȾY(ji)˾ؼԇ(yn)(yng)Է(yng)ߣc(dng)ԷνY(ji)˻н|
÷:ڷoˎ1.A(y)һ0.3gD2.ίcY(ji)ˎãwÿտڷ5mg/kg0.3gÿ15mg/kg900mgÿ23ͯ1.A(y)ÿհw10mg/kgһտ^(gu)0.3gD2.ίwÿ1020mg/kgÿղ^(gu)0.3gDijЩ(yn)ؽY(ji)˲(Y(ji)XĤ)ÿհwؿɸ_(d)30mg/kg(һ500mg)Ҫעιܓp܇(jng)İl(f)
ͨQ
Ƭ
Σ
?1.cY(ji)ˎ(lin)mڸͽY(ji)˲ίY(ji)XĤԼ֦UȾ
2.mڸͽY(ji)˲A(y)
(1)½_\Y(ji)˲ߵļͥɆTн|
(2)Y(ji)˾ؼԇ(yn)(PPD)(qing)(yng)ͬr(sh)زX侀zϷM(jn)ԽY(ji)˲̵^(gu)ȥδ^(gu)Ҏ(gu)Y(ji)ί
(3)ڽƄL(zhng)ڼίĻߣijЩѪҺW(wng)(ni)Ƥϵy(tng)(Ѫϲ)Yλθгg(sh)ȻY(ji)˾ؼԇ(yn)(yng)Է(yng)
(4)35q½Y(ji)˾ؼԇ(yn)(yng)ԵĻ
(5)֪ɞHIVȾY(ji)˾ؼԇ(yn)(yng)Է(yng)c(dng)ԷνY(ji)˻н|
÷
ڷoˎ
1.A(y)һ0.3gD
2.ίcY(ji)ˎwÿտڷ5mg/kg0.3gÿ15mg/kg900mgÿ23
ͯ
1.A(y)ÿհw10mg/kgһտ^(gu)0.3gD
2.ίwÿ1020mg/kgÿղ^(gu)0.3gDijЩ(yn)ؽY(ji)˲(Y(ji)XĤ)ÿհwؿɸ_(d)30mg/kg(һ500mg)Ҫעιܓp܇(jng)İl(f)
(yng)
l(f)^вB(ti)(wn)ľᘴ̸Ƹлָʹ(܇(jng))ɫۻƤwSȾ(ζ35qϻ߸ζl(f))ʳܛĻI(ζԵǰ(q)Y)l(f)ʘOҕģҕpϲϲʹ(ҕ(jng))l(f)ƤѪ(x)pټ鷿l(f)Ʒż(jng)ij鴤
ɣ
ιܲߣߺͰdB˽
ע(xing)
1.^(gu)(yng)(du)W(xu)Y(ji)(gu)P(gun)ˎ^(gu)Ҳ܌(du)Ʒ^(gu)
2.(du)\ĸɔ_~M(jn)ǜy(c)ɳʼ(yng)Է(yng)Ӱøy(c)ĽY(ji)¿ʹѪđtᰱD(zhun)øTᰱD(zhun)øĜy(c)ֵ
3.оdBʷ(yn)Iܓpߑ(yng)
4.篟гF(xin)ҕ(jng)װY(yng)M(jn)۲zڏ(f)
5.жr(sh)ôSB6(du)
ɷݣ
ƷҪɷ֞鮐
Ԡ
ƷɫƬ
ЋDڋDŮˎ
1.Ʒɴ^(gu)̥P(do)̥ѪˎȸĸѪˎ(dng)(sh)(yn)C(sh)¿̥mδC(sh)ЋD(yng)Õr(sh)횳֙(qun)cˎ(lin)ϕr(sh)(du)̥δU⣬ˎr(sh)(yng)^첻(yng)
2.֭Нȿ_(d)12mg/LcѪˎmȻδC(sh)І(wn)}g(yng)ԑ(yng)֙(qun)ˎtֹͣ
ͯˎ
(yn)ͯ÷ʹ
ˎ
50qϻñƷİl(f)^ߡ
ˎã
1.îr(sh)ÿƣƷTl(f)ĸKԷ(yng)ٮµĴx{(dio)µĄ^ζ(yng)滼߷ˎgƾ
2.XˎӾpٮ¿ڷʹѪˎȜpʑ(yng)ͬr(sh)ڿڷᄩǰ1Сr(sh)î¡
3.Ѫˎ(㶹ػMpͪ)cͬr(sh)(yng)Õr(sh)˿ˎøxʹ(qing)
4.ch(hun)zͬr(sh)И(jng)ϵy(tng)(yng)(^˯){(dio)^И(jng)ϵy(tng)䌦(du)ڏҪ`^ߵĹĻ
5.ƽcºÕr(sh)ӸζԵΣU(xin)ԣиιܓp?yn)鮐¿ߣگ̵^3(g)(yng)SLПo(w)ζF(xin)
6.SB6ӾSB6(jng)Ių܌(do)܇(jng)îr(sh)SB6Ҫ
7.cIƤ|(zh)(䝊)Õr(sh)Ӯڸ(ni)Ĵxй(do)ºѪˎȜpͶӰ푯Чڿ߸@(yng)m(dng){(dio)
8.c̫(alfentanil)Õr(sh)ڮˎøƄL(zhng)̫cp(disulfiram)ÿ(qing)И(jng)ϵy(tng)a(chn)ѣ(dng)f(xi){(dio)ʧߵȣcѺÿӾIԵğo(w)C(j)xγ
9.cY(ji)ˎɼغߵIJ(yng)cζˎÿӱƷĸζ˱M
10.²cͪ俵ʹߵѪˎȽ
11.cӢcAÕr(sh)ƶڸKеĴx(do)±ӢcAѪˎߣʮcȺ(yng)ûÕr(sh)ӢcAĄ(yng)m(dng){(dio)
12.c(du)ӺÕr(sh)ڮ¿Tμ(x)ɫP450ʹǰγɶԴxӸζԼI
13.cRƽͬr(sh)(yng)Õr(sh)¿xʹRƽѪˎߣԷ(yng)RƽT(do)µwxγɾиζԵgx
14.Ʒc(jng)ˎã(jng)
ˎã
ƷһNКõĺϳɿˎƷֻ(du)֦UҪL(zhng)ֳڵļ(x)ЧÙC(j)δUм(x)֦(mycolicacid)ĺϳɶʹ(x)ѡ
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ϺF(xin)ɭ ̩ô,ϺF(xin)ɭ ̩ôʹãt(y)ˎW(wng)ˎƷ(k)lṩϺF(xin)ɭ ̩f(shu),ϺF(xin)ɭ ̩Ƀr(ji),ϺF(xin)ɭ ̩ɶX,ϺF(xin)ɭ ̩ɵĹЧc...
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ϺF(xin)ɭ uAô,ϺF(xin)ɭ uAôʹt(y)ˎW(wng)ˎƷ(k)lṩϺF(xin)ɭ uAf(shu),ϺF(xin)ɭ uAr(ji),ϺF(xin)ɭ uAX,ϺF(xin)...
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~Q(mo) ô,~Q(mo) ôʹãt(y)ˎW(wng)ˎƷ(k)lṩ~Q(mo) f(shu),~Q(mo) r(ji),~Q(mo) X,~Q(mo) ĹЧc,~Q(mo) ...
KュI Ƭô,KュI Ƭôʹt(y)ˎW(wng)ˎƷ(k)lṩKュI Ƭf(shu),KュI Ƭr(ji),Kュ...